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To investigate the interrelationship between erythrocyte Na + /H + exchange rate and free cytosolic Ca 2+ concentration, the effect of the (non)selective protein kinase C inhibitors staurosporine, Ro 31-8220 and CGP 41251 (1 μmol/L) and of the protein kinase C activator phorbol-12-myristate-13-acetate (PMA, 1 μmol/L) was studied in vitro on these variables. PKC depleted...
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