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Neoaspergillic acid (NAA), a pyrazine hydroxamic acid, was produced by mixed cultures of two epiphytic fungi from a rotten fruit of mangrove Avicennia marina from the South China Sea. In the in vitro bioassays, NAA shows significant inhibitory activities against some Gram-positive and Gram-negative bacteria with MIC ranges of 0.49 – 15.62 µg/mL, and also exhibits moderate inhibitory activities against...
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