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In the rat, two distinct angiotensin II type 1a (rAT 1a ) receptor mRNAs are synthesized from a single rAT 1a receptor gene by alternative splicing. These two transcripts are comprised of exons 1, 2, and 3 (E1,2,3) or exons 1 and 3 (E1,3). Since exon 3 contains the entire coding region, both transcripts encode identical rAT 1a receptors. Real-time PCR revealed that in rat aortic...
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