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Basic characteristic feature of G-protein coupled receptors (GPCRs) is that they are differentially expressed in different cells in the human body. Orphan GPCRs endogenous substrates are unknown but they are reported to be involved as major drug targets in pharmaceuticals. Probable G-protein coupled receptor 139 (GPR139), belonging to class A GPCR, is present in humans and is encoded by GPR139 gene...
Stem prediction has been a problem that has attracted the attention of bioinformaticians for a long time. With important role in central dogma of prokarryotes and eukaryotes alike along with known role in viral genome encapsidation, the importance of DNA/RNA stems cannot be neglected. Bacterial interspersed Mosaic Elements known as BIMEs play an important regulatory role in bacterial replication....
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