The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
The basal ganglia play an important role in motor control and their malfunction is implicated in several disorders including Parkinson's disease (PD), in which dopamine concentration is greatly reduced. This is associated with changes in their firing patterns, evidenced by increase in firing rate of output nuclei of basal ganglia and synchronization between neurons of different micro-circuitry of...
In this work we propose a biophysical neural network model to investigate some of the impacts of the Alzheimer's disease (AD) on spatial navigation in a simulated rodent. The model is a hybrid model developed based on physiological and functional description of neuronal networks in the hippocampus engaged in place field formation. The model of hippocampal network takes into account both anatomical...
Schizophrenia is a severe chronic psychiatric disorder and its pathology is still not completely known. However, up to now several different theories have been proposed to describe the pathophysiology of schizophrenia. Hypofunction of NMDA receptors (NMDAR) and inactivated astrocytes are among important glutamatergic theories explaining the pathophysiology of schizophrenia. On the other hand, it has...
There is physiological evidence that Central Pattern Generators (CPG's), at the level of spinal cords, are responsible for generating rhythmic movements in some species of animals like salamanders. There are also other researches suggesting that in human beings there are CPGs at higher levels of the Central Nervous System (CNS) which facilitate the control of rhythmic movements. We proposed a model...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.