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Abstract We examined the different vasodilatory effects of the K+ channel openers levcromakalim and 5-amino-N-[2-(2-chlorophenyl)ethyl]-N-cyano-3-pyridinecarboxamidine (KRN4884), and the Ca2+ channel blocker nifedipine in the rat aorta. KRN4884 (1010105M) and nifedipine (1010105M) produced concentration-dependent relaxation in the rat aorta precontracted by 25mMKCl. The K+ channel blocker glibenclamide...
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