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Transforming growth factor-β1 (TGF-β1) plays a crucial role in adhesion and migration of human cancer cells. Besides, integrins are the major adhesive molecules in mammalian cells. Here we found that TGF-β1 increased the migration and cell surface expression of β1 integrin in human lung cancer cells (A549 cells). TGF-β1 stimulation increased phosphorylation of p85α subunit of phosphatidylinositol...
It has been shown that ultrasound (US) stimulation accelerates fracture healing in the animal models and in clinical studies. However, the precise molecular events generated by US in chondrocytes have not been clarified well. Here we found that US stimulation transiently increased the surface expression of α2, α5, β1 or β3 but not α3 or α4 integrins in human chondrocytes, as shown by flow cytometric...
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