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The superficial laminae of the spinal cord are crucial sites for the transmission of incoming noxious information. Calcitonin gene-related peptide (CGRP) is released from the presynaptic nerve terminals in these laminae. One of the objectives was to evaluate the temporospatial pattern of expression of CGRP following paw incision in rats. Paw incision-induced nociception mimics postoperative pain in...
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