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The development of digital bioprocessing technologies is critical to operate modern industrial bioprocesses. This study conducted the first investigation on the efficiency of using physics‐based and data‐driven models for the dynamic optimisation of long‐term bioprocess. More specifically, this study exploits a predictive kinetic model and a cutting‐edge data‐driven model to compute open‐loop optimisation...
Lutein is a high‐value bioproduct synthesized by microalga Desmodesmus sp. In the current study two aspects of this process are thoroughly investigated: identifying the complex effects of light intensity and nitrate concentration on biomass growth and lutein synthesis, and constructing an accurate kinetic model capable of simulating the entire bioprocess dynamic performance, neither of which has been...
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