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Background
For specific clinical indications, androgen deprivation therapy (ADT) will induce disease prostate cancer (PC) regression, relieve symptoms and prolong survival; however, ADT has a well‐described range of side effects, which may have a detrimental effect on the patient's quality of life, necessitating additional interventions or changes in PC treatment. The risk‐benefit analysis for initiating...
BACKGROUNDExtended transrectal ultrasound guided biopsies (TRUSB) of the prostate may not accurately convey true morphometric information and Gleason score (GS) of prostate cancer (PCa) and the clinical use of template‐guided (5‐mm grid) transperineal mapping biopsies (TPMBs) remains controversial.
METHODSWe correlated the clinical‐pathologic results of 1,403 TPMB cores obtained from 25 men diagnosed...
BACKGROUNDSilibinin is a polyphenolic flavonolignan derived from milk thistle (Silybum marianium) with anti‐oxidant properties. The purpose of the current trial was to determine the tissue and blood effects of high‐dose silybin‐phytosome in prostate cancer patients.
METHODSSubjects with localized prostate cancer planning for a prostatectomy were eligible to enroll. Six patients received 13 g of silybin‐phytosome...
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