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The neuromuscular junction (NMJ) is the synapse between the axon terminal of motoneuron and the ‘endplate’ of a muscle fiber. The nerve impulse leads to a large depolarization called the endplate potential, which in turn opens a large number of voltage-sensitive sodium channels located within post-junctional synaptic folds. This set off causing an ‘all or nothing’ action potential that is propagated...
The Neuromuscular Junction (NMJ) is the place where one end plate terminal of a motor neuron forms a synapse with a muscle fiber. Unlike synapses between neurons, the NMJ is characterized by a large number of voltage-dependent sodium channels located within post-junctional folds of the muscle fiber membrane. In this work we have used a mathematical model to simulate the behavior of the voltage-dependent...
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