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The paper introduces an Extended Kalman Smoother (EKS) for T-wave alternans (TWA) detection, based on a dynamical model which is not directly dependent on amplitude (EKS3). In this framework we consider separate states for PQRS and an amplitude-free state model for T-wave. There are some theoretical advantages that EKS3 has over other frameworks recently introduced with the same aims (e.g., EKS6-4obs,...
Morphological modelling of electrocardiographical P-waves could simplify the detection of signals' morphological features employed in risk stratification. We compared four different approaches, based on signal decomposition, for morphological modeling of signal-averaged P waves. The functional models included: trigonometric, Bézier, B-spline, and Gaussian basis functions.
Drug-induced alterations of ventricular heterogeneity must be limited to avoid induction of lethal ventricular arrhythmias. In here, a new parameter called V-index, able to measure the standard deviation of myocites' repolarization times, was evaluated after moxifloxacin administration. 24-h Holter ECGs of 68 healty subjects enrolled for a thorough QT study were retrospectively analyzed. The placebo...
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