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Neutrophils play an important role against bacterial infection, mainly methicillin resistant Staphylococcus aureus (MRSA). Therefore, we developed an animal model to simultaneously monitor bacterial colonization and neutrophil migration in vivo. Using lys-EGFP C57BL/6 mice, we initially rendered the mice temporally neutropenic using cyclophosphamide (CPM) treatment (300mg/kg or 375mg/kg). Later, bioluminescent...
To study the relationship of the presence of secondary SS with disease activity, duration in RA.Eighty two patients with RA were submitted to Schirmer test, minor salivary gland biopsy, questionnaire on sicca symptoms, DAS-28 4v determination.In this population, 20 (24.3%) patients fulfilled the American-European classification criteria for secondary SS. No relation could be found between the presence...
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