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Einzelzellanalyse Eine auf einer duplexspezifischen Nuklease basierende Nanopipette wurde im Forschungsartikel auf S. 13352 von Wei‐Wei Zhao, Jing‐Juan Xu et al. hergestellt und zur Analyse der wirkstoffinduzierten Schwankung des miR‐10b‐Spiegels auf Einzelzellniveau verwendet.
New tools for single‐cell interrogation enable deeper understanding of cellular heterogeneity and associated cellular behaviors and functions. Information of RNA expression in single cell could contribute to our knowledge of the genetic regulatory circuits and molecular mechanism of disease development. Although significant progresses have been made for intracellular RNA analysis, existing methods...
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