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Self‐Boosting Vaccination
In article number 2207892, Xiang Gao, Bo Liu, Jing Gao, and co‐workers propose a pulsatile antigen released core‐shell microparticle namely LbL/MPs to achieve self‐boosting vaccination after single‐injection and to simulate multi‐injection immunization. LbL/MPs show multiple antigen release characteristics and can effectively induce immune response. The core‐shell microstructure...
Vaccination is among the most effective ways to prevent infectious diseases. Subunit vaccines are safe but usually require multiple booster shots, which may lead to immunity loss and economic consume. In this study, a self‐boosting vaccine is developed based on the pulsatile release of antigen from the core–shell microparticle after single‐injection immunization. Self‐healing technology applied to...
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