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Traumatic brain injury in elderly patients is a neglected global disease burden. The main cause is fall, followed by motor vehicle accidents. This review article summarizes different aspects of geriatric traumatic brain injury, including epidemiology, pathology, and effects of comorbidities and pre-injury medications such as antiplatelets and anticoagulants. Functional outcome with or without surgical...
Real-time tagless monitoring of cell viability using patch-clamp microdevices is reported and validated by using fluorescence imaging techniques for the first time. Specifically, human breast cancer cells MDA-MB-231 have been used for these studies. Systematic experiments on these cells found that the impedance change of captured cells by the micro-electrodes is a valid indicator of cell's living...
This paper reports the analysis of drug effects on single breast cancer cells using the droplet-microfluidic devices for the first time. Hundreds of droplets can be generated in less than 5 minutes. Each droplet serves as a nanoliter-volume titer plate. About 50% of the droplets contain a human breast cancer cell MDA-MB-231 and Cytochalasin D drug solution. The drug effects on each cell are monitored...
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