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ObjectivesWe investigated the association between mRNA levels, polymorphisms of Kallikrein7 (KLK7) and Kallikrein10 (KLK10), and the development of oral squamous cell carcinoma (OSCC).
Materials and methodsWe recruited 217 OSCC patients and 138 healthy controls. All were men, betel quid chewers, cigarette smokers, and Minnan ethnicity. Genotyping was performed using a TaqMan® probe genotyping assay...
Oral Diseases (2011) 17, 283–290
Objective: S100A2, a Ca2+ ‐binding protein with two EF‐hands, is a tumor suppressor in oral cancer. Helix III flanking the C‐terminal EF‐hand is implicated to participate in the interaction of S100A2 and its target(s). The aim of this study was to examine if the coding sequence polymorphism S100A2_185G>A, leading to the peptide 62 substitution of asparagine (AAC,...
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