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Peripheral amyloidosis is a debilitating and often fatal disease. SPECT imaging of amyloid in mice has been established using 125I-SAP. Current efforts are aimed at using125I-labeled synthetic peptides such as p5, which are easier to translate into the clinic in the US since SAP is of human origin. It needs to be shown that the new peptide biomarkers correlate well with the gold standard, SAP. As...
Transmission measurements are performed on PET tomographs to create attenuation correction factors for quantitatively accurate images. There are several opportunities within the Inveon Dedicated PET (DPET) to improve the overall performance of the system. The transmission mechanism has a number of characteristics that make it suitable for conebeam-like reconstruction techniques similar to those used...
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