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In this work, a novel methodology of evaluating the glycan distribution has been proposed. A multivariate statistical regression method of partial least squares (PLS) is used to establish the relationship between the manipulated variables and the response variables. All the fitting relations are contained in the glycosylation process gain matrix K obtained by PLS. According to the singular value decomposition...
A non-parameter modeling methodology for the online dynamically modeling of nonlinear neuromuscular blockade (NMB) is presented in this paper. A big challenge of modeling NMB is the responses from muscular are quite different from people to people and the individual dynamic may change during the procedure of operation. Gaussian process (GP) is a kind of probabilistic and non-parametric modeling method...
Basing on the kinetic model analysis of cell metabolism network can visualize the movement of intracellular metabolism, and provide the link between cell culture and manufacture of biological products. The kinetic model reconstruction in silico of nucleotide sugar donor (NSD) metabolic network has been put forward by Philip et al., which involved with 34 metabolites mass balances and 60 metabolic...
Building models and model mesh simplification multiresolution storage mechanism is the key for three-dimensional navigation widely used. This paper proposed a mesh simplification and multiresolution storage compression algorithm based on the model of edge collapse operations. First of all, it used an artificial interact method to set the protected feature points and grids and updated a series of partial...
To investigate the relationship among the fractal dimension, the combustion degree, and the stability of flame in supersonic combustion, photos of OHldr radicals spontaneity radiation were taken and the large Eddy simulation was used to calculate supersonic hydrogen combustion. As cavity is the flame holder in strongly turbulent supersonic combustion, different structural cavities were studied via...
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