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The DNA recombination process known as V(D)J recombination is the central mechanism for generating diversity among antigen receptors such as T-cell receptors (TCRs). This diversity is crucial for the development of the adaptive immune system. However, modeling of all the alpha beta TCR sequences is encumbered by the enormity of the potential repertoire, which has been predicted to exceed 10^15 sequences...
Program development environments have enabled graphics processing units (GPUs) to become an attractive high performance computing platform for the scientific community. A commonly posed problem in computational biology is protein database searching for functional similarities. The most accurate algorithm for sequence alignments is Smith-Waterman (SW). However, due to its computational complexity and...
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