Search results for: M. Musser

Items from 1 to 20 out of 105 results

article

Survey of Salmonella in raw tree nuts at retail in the United States

Guodong Zhang, Lijun Hu, Yan Luo, Sofia M Santillana Farakos, more

Journal of Food Science > 86 > 2 > 495 - 504

Abstract The objective of this survey was to estimate the prevalence, contamination level, and genetic diversity of Salmonella in selected raw, shelled tree nuts (Brazil nuts, cashews, hazelnuts, macadamia nuts, pecans, pine nuts, pistachios, and walnuts) at retail markets in the United States. A total of 3,374 samples of eight tree nuts were collected from different types of retail stores and markets...

article

Loss and gain of cone types in vertebrate ciliary photoreceptor evolution

Jacob M. Musser, Detlev Arendt

Developmental Biology > 2017 > 431 > 1 > 26-35

Ciliary photoreceptors are a diverse cell type family that comprises the rods and cones of the retina and other related cell types such as pineal photoreceptors. Ciliary photoreceptor evolution has been dynamic during vertebrate evolution with numerous gains and losses of opsin and phototransduction genes, and changes in their expression. For example, early mammals lost all but two cone opsins, indicating...

article

Development of a self-assembling protein nanoparticle vaccine targeting Plasmodium falciparum Circumsporozoite Protein delivered in three Army Liposome Formulation adjuvants

Labdhi Seth, Karen M. Bingham Ferlez, Stephen A. Kaba, Derek M. Musser, more

Vaccine > 2017 > 35 > 41 > 5448-5454

We have developed FMP014, a vaccine candidate against Plasmodium falciparum malaria, which is comprised of 60 identical monomer protein chains that form an icosahedral shaped self-assembling protein nanoparticle (SAPN). Each monomer contains selected P. falciparum Circumsporozoite Protein (PfCSP) CD4+ and CD8+ epitopes, universal T_H epitopes, portions of the α-TSR domain, and 6 repeats of the NANP...

article

Contribution of Secreted NADase and Streptolysin O to the Pathogenesis of Epidemic Serotype M1 Streptococcus pyogenes Infections

Luchang Zhu, Randall J. Olsen, Jessica D. Lee, Adeline R. Porter, more

The American Journal of Pathology > 2017 > 187 > 3 > 605-613

Streptococcus pyogenes secretes many toxins that facilitate human colonization, invasion, and dissemination. NADase (SPN) and streptolysin O (SLO) are two toxins that play important roles in pathogenesis. We previously showed that increased production of SPN and SLO in epidemic serotype M1 and M89 S. pyogenes strains is associated with rapid intercontinental spread and enhanced virulence. The biological...

article

Deciphering the Structure and Function of Nuclear Pores Using Single-Molecule Fluorescence Approaches

Siegfried M. Musser, David Grünwald

Journal of Molecular Biology > 2016 > 428 > 10(PA) > 2091-2119

Due to its central role in macromolecular trafficking and nucleocytoplasmic information transfer, the nuclear pore complex (NPC) has been studied in great detail using a wide spectrum of methods. Consequently, many aspects of its architecture, general function, and role in the life cycle of a cell are well understood. Over the last decade, fluorescence microscopy methods have enabled the real-time...

article

Structural and functional analysis of RopB: a major virulence regulator in Streptococcus pyogenes

Nishanth Makthal, Maire Gavagan, Hackwon Do, Randall J. Olsen, more

Molecular Microbiology > 99 > 6 > 1119 - 1133

Group A Streptococcus (GAS) is an exclusive human pathogen that causes significant disease burden. Global regulator RopB of GAS controls the expression of several major virulence factors including secreted protease SpeB during high cell density. However, the molecular mechanism for RopB‐dependent speB expression remains unclear. To understand the mechanism of transcription activation by RopB, we determined...

chapter

Spectrum sensing with WLAN access points

Ryan T. Jacobs, Jason B. Coder, Vivian M. Musser

2016 United States National Committee of URSI National Radio Science Meeting (USNC-URSI NRSM) > 1 - 2

2016 United States National Committee of URSI National Radio Science Meeting (USNC-URSI NRSM)

With wireless communication becoming increasingly common in simple everyday devices, the available spectrum is quickly filling up and the risk of interference is increasing. This interference could be a slight nuisance or a disruption to critical services. To better understand the quantity and type of traffic in congested environments, a potential spectrum sensing solution in the ISM bands is discussed...

chapter

Examples of high-speed harmonic load pull investigations of high-efficiency GaN power transistors

M. Marchetti, T. Maier, V. Carrubba, S. Maroldt, more

2015 IEEE International Conference on Microwaves, Communications, Antennas and Electronic Systems (COMCAS) > 1 - 4

2015 IEEE International Conference on Microwaves, Communications, Antennas and Electronic Systems (COMCAS)

This paper presents the capability of an advanced and high-speed, mixed-signal active harmonic load-pull system through measurement activity on AlGaN/GaN transistors. The advantages of the GaN technology which can provide a high power density and a high efficiency are best exploited when the optimum fundamental and harmonic terminations are provided to the transistor. The ultra-high speed of the system,...

chapter

A dual-band UMTS/LTE highly power-efficient Class-ABJ Doherty GaN PA

V. Carrubba, E. Ture, S. Maroldt, M. Musser, more

2015 European Microwave Conference (EuMC) > 1164 - 1167

2015 European Microwave Conference (EuMC 2015)

This paper reports on the realization of a dual-band high power Class-ABJ GaN Doherty power amplifier (PA) for base-station transmitter system (BTS) applications. The designed Doherty PA module consists of two individual single-ended high power-efficient AlGaN/GaN PAs with multi-harmonic Class-ABJ termination operating in both UMTS 2.1–2.2 GHz and LTE 2.6–2.7 GHz communication bands. Measurements...

article

High-Efficiency, High-Temperature Continuous Class-E Sub-Waveform Solution AlGaN/GaN Power Amplifier

V. Carrubba, S. Maroldt, M. Musser, E. Ture, more

IEEE Microwave and Wireless Components Letters > 2015 > 25 > 8 > 526 - 528

This letter presents the realization of a high-efficiency, high-temperature Continuous Class-E Sub-Waveform Solution power amplifier using for the first time GaN technology. The recently introduced Continuous Class-E PA mode theory has revealed new and various impedance solutions for which high efficiency switch mode PAs can be realized. The investigation carried out in this work clearly shows that...

article

Molecular Pathogenesis Lessons from the World of Infectious Diseases Research

James M. Musser, Frank R. DeLeo

The American Journal of Pathology > 2015 > 185 > 6 > 1502-1504

This Guest Editorial introduces this month's special Infectious Disease Theme Issue, a series of reviews focusing on the molecular pathogenic processes of four representative pathogens, including two bacteria (brucellae and Staphylococcus aureus), a virus (influenza), and a parasite (Trypanosoma cruzi).

article

Nuclear β‐catenin localization supports homology of feathers, avian scutate scales, and alligator scales in early development

Jacob M. Musser, Günter P. Wagner, Richard O. Prum

Evolution & Development > 17 > 3 > 185 - 194

Feathers are an evolutionary novelty found in all extant birds. Despite recent progress investigating feather development and a revolution in dinosaur paleontology, the relationship of feathers to other amniote skin appendages, particularly reptile scales, remains unclear. Disagreement arises primarily from the observation that feathers and avian scutate scales exhibit an anatomical placode—defined...

chapter

Analysis and performance of drain bias “in-dependent” Class-J power amplifier

V. Carrubba, E. Ture, R. Quay, F. van Raay, more

2014 Asia-Pacific Microwave Conference > 998 - 1000

2014 Asia-Pacific Microwave Conference (APMC)

This paper presents a broadband high power-efficiency Class-J PA investigation as a function of drain bias voltage V_DC. The Class-J PA mode concept for which high power-efficiencies are released for the wideband frequency spectrum has been so far investigated for fixed V_DC. In this paper for the first time the Class-J approach has been investigated as a function of the supply drain voltage. The experimental...

article

Comparative Whole Genome Sequencing of Community‐Associated Methicillin‐Resistant Staphylococcus aureus Sequence Type 8 from Primary Care Clinics in a Texas Community

Grace C. Lee, S. Wesley Long, James M. Musser, Stephen B. Beres, more

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy > 35 > 2 > 220 - 228

Study ObjectiveOur understanding of the molecular dynamics driving the community‐associated methicillin‐resistant Staphylococcus aureus (CA‐MRSA) epidemic at the whole genome level is limited. We sought to assess the use of whole genome sequencing (WGS) to evaluate the genomic diversity and genotypic prediction of antimicrobial resistance of CA‐MRSA isolates from patients in South Texas. DesignComparative...

article

A Naturally Occurring Single Amino Acid Replacement in Multiple Gene Regulator of Group A Streptococcus Significantly Increases Virulence

Misu Sanson, Brian E. O'Neill, Priyanka Kachroo, Jeff R. Anderson, more

The American Journal of Pathology > 2015 > 185 > 2 > 462-471

Single-nucleotide polymorphisms (SNPs) are the most common source of genetic variation within a species; however, few investigations demonstrate how naturally occurring SNPs may increase strain virulence. We recently used group A Streptococcus as a model pathogen to study bacteria strain genotype–patient disease phenotype relationships. Whole-genome sequencing of approximately 800 serotype M59 group...

chapter

Broadband 1.7–2.8 GHz high-efficiency (58%), high-power (43 dBm) Class-BJ GaN power amplifier including package engineering

E. Ture, V. Carrubba, S. Maroldt, M. Musser, more

2014 44th European Microwave Conference > 1289 - 1292

2014 44th European Microwave Conference (EuMC)

In this paper a broadband high-efficiency Class-BJ GaN HEMT-PA for wireless communication applications is realized. Influences of packaging and bond wires on the PA performance are investigated in order to demonstrate and use accurate package models. A novel optimization of bond wires for packaged powerbars is therefore performed and, subsequently a fully characterized PA is effectively designed....

article

Brain and behaviour of living and extinct echidnas

Ken W.S. Ashwell, Craig D. Hardman, Anne M. Musser

Zoology > 2014 > 117 > 5 > 349-361

The Tachyglossidae (long- and short-beaked echidnas) are a family of monotremes, confined to Australia and New Guinea, that exhibit striking trigeminal, olfactory and cortical specialisations. Several species of long-beaked echidna (Zaglossus robusta, Zaglossus hacketti, Megalibgwilia ramsayi) were part of the large-bodied (10kg or more) fauna of Pleistocene Australasia, but only the diminutive (2–7kg)...

article

Integrating rapid diagnostics and antimicrobial stewardship improves outcomes in patients with antibiotic-resistant Gram-negative bacteremia

Katherine K. Perez, Randall J. Olsen, William L. Musick, Patricia L. Cernoch, more

Journal of Infection > 2014 > 69 > 3 > 216-225

An intervention for Gram-negative bloodstream infections that integrated mass spectrometry technology for rapid diagnosis with antimicrobial stewardship oversight significantly improved patient outcomes and reduced hospital costs. As antibiotic resistance rates continue to grow at an alarming speed, the current study was undertaken to assess the impact of this intervention in a challenging patient...

article

Mycobacterium tuberculosis bacteraemia: experience from a non‐endemic urban centre

H. M. El Sahly, L. D. Teeter, J. M. Musser, E. A. Graviss, more

Clinical Microbiology and Infection > 20 > 3 > 263 - 268

The isolation of Mycobacterium tuberculosis from blood culture specimens has been associated with human immunodeficiency virus (HIV) co‐infection with variable impact on tuberculosis (TB) mortality reported. The overwhelming majority of M. tuberculosis bacteraemia cases were described in developing countries. We present a nested case–control analysis of clinical, sociodemographic and behavioural risk...

article

Evaluation of large genotypic Mycobacterium tuberculosis clusters: contributions from remote and recent transmission

Larry D. Teeter, Ngan P. Ha, Xin Ma, Jane Wenger, more

Tuberculosis > 2013 > 93 > Supplement > S38-S46

Tuberculosis genotypic clustering is used as a proxy for recent transmission. The association between clustering and recent transmission becomes problematic when the genotyping method lacks specificity in defining a cluster, as well as for clusters with extensive jurisdictional histories and/or common genotypes. We investigated the four largest spoligotype/12 loci MIRU-VNTR-defined clusters in Harris...

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GALLIUM NITRIDE (8)
BROADBAND AMPLIFIERS (6)
POWER AMPLIFIERS (6)
TUBERCULOSIS (6)
GAIN (5)
GALLIUM COMPOUNDS (5)
CLASS-J (4)
HIGH ELECTRON MOBILITY TRANSISTORS (4)
ALUMINIUM COMPOUNDS (3)
FREQUENCY MEASUREMENT (3)
GAN HEMT (3)
HARMONIC ANALYSIS (3)
III-V SEMICONDUCTORS (3)
POWER GENERATION (3)
STREPTOCOCCUS PYOGENES (3)
ALGAN-GAN (2)
ALGAN/GAN (2)
ALUMINUM GALLIUM NITRIDE (2)
BROADBAND APPLICATIONS (2)
BROADBAND POWER AMPLIFIER (2)
COMMUNICATION JAMMERS (2)
DNA MICROARRAY (2)
ELECTRON TRANSFER (2)
EPIDEMIOLOGY (2)
FREQUENCY 2 GHZ TO 6 GHZ (2)
GAN (2)
GIS (2)
GROUP A STREPTOCOCCUS (2)
HEMT (2)
HEMT TECHNOLOGY (2)
HEMTS (2)
HIGH POWER AMPLIFIERS (2)
HPA (2)
IMPEDANCE (2)
INCIDENCE (2)
MICROWAVE POWER AMPLIFIERS (2)
MICROWAVE TRANSISTORS (2)
MMIC POWER AMPLIFIERS (2)
MORTALITY (2)
MULTIBAND (2)
NUCLEAR PORE COMPLEX (2)
NUCLEAR TRANSPORT (2)
POWER AMPLIFIER MODULE (2)
POWER AMPLIFIERS (PAS) (2)
PROTON PUMPING (2)
PUBLIC TRANSPORTATION (2)
RELIABILITY (2)
SINGLE MOLECULE FLUORESCENCE (2)
SUBSTRATES (2)
SURVEILLANCE (2)
TB CONTROL (2)
UBIQUINOL OXIDASE (2)
UHF POWER AMPLIFIERS (2)
VOLTAGE 50 V (2)
WIDE BAND GAP SEMICONDUCTORS (2)
WIDEBAND AMPLIFIERS (2)
STAPHYLOCOCCUS AUREUS (1)
1918 INFLUENZA VIRUS (1)
ACONITASE (1)
ACTIVE ELECTRONICALLY SCANNED ARRAY (1)
ACTIVE ELECTRONICALLY SCANNED ARRAY EW SYSTEMS (1)
ADJUVANT (1)
AL-GAN-GAN (1)
ALUMINIUM (1)
ANSAMYCIN (1)
ANTIMICROBIAL RESISTANCE (1)
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AVIUM (1)
BACTERIA (1)
BACTERIAL PATHOGENS (1)
BACTERIOPHAGE (1)
BILIARY EXCRETION (1)
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BREVETOXIN (1)
BREVETOXIN METABOLISM (1)
BROADBAND HIGH POWER AMPLIFIERS (1)
CELL IMAGING (1)
CHANNEL TEMPERATURE (1)
CHROMATOGRAPHIC SEPARATION (1)
CLASS-E (1)
CLUSTER (1)
CNS (1)
CO-ELUTION (1)
COMPARATIVE GENOMICS (1)
CPOE (1)
CYTOCHROME C OXIDASE (1)
CYTOCHROME C OXIDASE UBIQUINOL OXIDASE NITRIC OXIDE REDUCTASE PROTON PUMP Q(H2)-LOOP EVOLUTIONARY TREE RESPIRATORY EFFICIENCY RESPIRATORY COMPLEXITY (1)
CYTOCHROME OXIDASE (1)
CYTOTOXICITY (1)
DECISION SUPPORT SYSTEMS (1)
DISCRIMINANT BASED CHARGE DECONVOLUTION (1)
DISSEMINATED (1)
DIVERSITY (1)
DOHERTY AMPLIFIER (1)
EASTERN OYSTER (1)
EFFICIENCY 59 PERCENT (1)
ELECTRONIC HEALTH RECORDS (1)
ELECTRONIC WAREFARE APPLICATIONS (1)
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Chemical Research in Toxicology (1)
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Current Psychology (1)
Developmental Biology (1)
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European Journal of Clinical Microbiology & Infectious Diseases (1)
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IEEE Microwave and Wireless Components Letters (1)
International Journal of Infectious Diseases (1)
International Journal of Medical Informatics (1)
Journal of Food Science (1)
Journal of Investigative Dermatology (1)
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Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy (1)
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INFONA - science communication portal

Search results for: M. Musser

Survey of Salmonella in raw tree nuts at retail in the United States

Loss and gain of cone types in vertebrate ciliary photoreceptor evolution

Development of a self-assembling protein nanoparticle vaccine targeting Plasmodium falciparum Circumsporozoite Protein delivered in three Army Liposome Formulation adjuvants

Contribution of Secreted NADase and Streptolysin O to the Pathogenesis of Epidemic Serotype M1 Streptococcus pyogenes Infections

Deciphering the Structure and Function of Nuclear Pores Using Single-Molecule Fluorescence Approaches

Structural and functional analysis of RopB: a major virulence regulator in Streptococcus pyogenes

Spectrum sensing with WLAN access points

Examples of high-speed harmonic load pull investigations of high-efficiency GaN power transistors

A dual-band UMTS/LTE highly power-efficient Class-ABJ Doherty GaN PA

High-Efficiency, High-Temperature Continuous Class-E Sub-Waveform Solution AlGaN/GaN Power Amplifier

Molecular Pathogenesis Lessons from the World of Infectious Diseases Research

Nuclear β‐catenin localization supports homology of feathers, avian scutate scales, and alligator scales in early development

Analysis and performance of drain bias “in-dependent” Class-J power amplifier

Comparative Whole Genome Sequencing of Community‐Associated Methicillin‐Resistant Staphylococcus aureus Sequence Type 8 from Primary Care Clinics in a Texas Community

A Naturally Occurring Single Amino Acid Replacement in Multiple Gene Regulator of Group A Streptococcus Significantly Increases Virulence

Broadband 1.7–2.8 GHz high-efficiency (58%), high-power (43 dBm) Class-BJ GaN power amplifier including package engineering

Brain and behaviour of living and extinct echidnas

Integrating rapid diagnostics and antimicrobial stewardship improves outcomes in patients with antibiotic-resistant Gram-negative bacteremia

Mycobacterium tuberculosis bacteraemia: experience from a non‐endemic urban centre

Evaluation of large genotypic Mycobacterium tuberculosis clusters: contributions from remote and recent transmission

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