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In the present study, the participation of protein kinase C (PKC) signalling in prothoracicotropic hormone (PTTH)‐stimulated ecdysteroidogenesis in Bombyx prothoracic glands (PGs) is demonstrated and characterized. PTTH stimulated phosphorylation of a 37‐kDa protein in Bombyx PGs both in vitro and in vivo, as recognized by a PKC substrate antibody. Treatment with either A23187 or thapsigargin also...
It is well known that phosphorylation of extracellular signal‐regulated kinase (ERK) is involved in prothoracicotropic hormone (PTTH)‐stimulated ecdysteroidogenesis in insect prothoracic glands (PGs). In the present study, we further investigated the downstream signalling pathways. Our results showed that PTTH stimulated p90 ribosomal S6 kinase (RSK) phosphorylation at Thr573 in Bombyx mori PGs both...
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