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We demonstrate a diagnostics platform which integrates an ISFET array and a temperature control loop for isothermal DNA detection. The controller maintains a temperature of 63°C to perform nucleic acid amplification which is detected by the on-chip sensors. The 32×32 ISFET array is first calibrated to cancel trapped charge and then measures the change in the pH of the reaction. The sensor data is...
This paper presents a novel scalable readout-converter operating in weak inversion with a least significant bit resolution of 0.015pH change. The readout-converter eliminates the effect of temperature on measurements and suppresses the influence of sensing membrane buffer capacity as well as the transistor slope factor variation when in weak inversion. With the ISFET floating-gate resetting, there...
In this paper, the experimental results of a complete battery-less wirelessly-powered 2.45-GHz temperature sensor system with a microcontroller and an ISM-band transmitter on FR-4 is presented. As the measured results show, the energy harvesting system can provide 2.4 V to turn on the , temperature sensor and transmitter with only radio...
In this paper, we present a novel, ultra-long-time-constant analogue integrator for a PID controller in Lab-on-Chip (LOC) applications. A time constant of up to 5 seconds is achievable using a capacitance of only 18pF by exploiting transconductance reduction techniques involving current splitting and gm-attenuated OTA. Additionally, this architecture provides the ability to digitally tune the time...
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