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In this study, we quantified the depolarization, as a function of depth, induced by scattering in tissue-simulating optical phantoms using polarization-sensitive optical coherence tomography (PS-OCT). The preliminary results indicate that the PS-OCT may be suitable for diagnosis of diseases that causes the scattering changes.
Scattering changes inside turbid media can be quantified using the polarization-sensitive optical coherence tomography (PS-OCT) which measures the degree of circular polarization (DOCP) as a function of depth. We have tested our hypothesis using Intralipid phantoms and successfully applied this technique for diagnosis of cervical interepithelial neoplasm (CIN).
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