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The ambient electrochemical N2 reduction reaction (NRR) is a future approach for the artificial NH3 synthesis to overcome the problems of high‐energy consumption and environmental pollution by Haber–Bosch technology. However, the challenge of N2 activation on a catalyst surface and the competitive hydrogen evolution reaction make the current NRR unsatisfied. Herein, this work demonstrates that NbB...
3D bioprinting has become a flexible technical means used in many fields. Currently, research on 3D bioprinting is mainly focused on the use of mammalian cells to print organ and tissue models, which has greatly promoted progress in the fields of tissue engineering, regenerative medicine, and pharmaceuticals. In recent years, bacterial bioprinting has gradually become a rapidly developing research...
Neuroblastoma Therapy
In article number 2201671, Zhen Liu and co‐workers construct polysialic acid‐targeting nano‐missiles via a molecular imprinting strategy using oligosialic acid containing 4‐7 units digested from polySia as the template. Effective targeted photothermal therapy of neuroblastoma is achieved using nano‐missiles loaded with the near‐infrared fluorescent reactive dye indocyanine green...
Exploring new targets and developing novel targeted therapies are urgently needed for neuroblastoma therapy. Polysialic acid (polySia), a linear homopolymer of sialic acid units that correlates well with tumor progression and poor prognosis, has emerged as a potential target for neuroblastoma. However, the lack of polySia‐specific binding reagents has severely limited the development of polySia‐targeting...
In article number 2002169, Wu Wei, Yan Li, Tiangang Liu, and co‐workers develop a novel detection technology, nanopore targeted sequencing (NTS), for the accurate and comprehensive detection of SARS‐CoV‐2 and other respiratory viruses. This detection technology is suitable for the identification of suspected COVID‐19 cases and can also monitor mutations in the virus and the type of virus.
The ongoing global novel coronavirus pneumonia COVID‐19 outbreak has engendered numerous cases of infection and death. COVID‐19 diagnosis relies upon nucleic acid detection; however, currently recommended methods exhibit high false‐negative rates and are unable to identify other respiratory virus infections, thereby resulting in patient misdiagnosis and impeding epidemic containment. Combining the...
The requirement of nontoxic and versatile manufacturing frameworks for biologically relevant applications has imposed significant constraints on the choice of functional materials and the complementary fabrication tools. In this context, silk is actively studied, thanks to its mechanical robustness, biocompatibility, wide availability, aqueous processing conditions, and ease of functionalization....
In article number 1802953, Tiger H. Tao and co‐workers report a silk‐based water lithography technique. This work introduces a wafer‐scale, all‐water‐based, chemical‐free, biopatterning method that allows for rapid prototyping of biologically functional devices and interfaces in an extremely fast fashion, and importantly, in ambient conditions, on both planar and curved surfaces.
Lead Iodide (PbI2) is a layered semiconductor with direct band gap holding great promises in green light emission and detection devices. Recently, PbI2 planar lasers are demonstrated using hexagonal whispering‐gallery‐mode microcavities, but the lasing threshold is quite high. In this work, lasing from vapor phase deposition derived PbI2 trapezoidal nanoplatelets (NPs) with threshold that is at least...
A novel anode material for lithium‐ion batteries derived from aromatic imides with multicarbonyl group conjugated with aromatic core structure is reported, benzophenolne‐3,3′,4,4′‐tetracarboxylimide oligomer (BTO). It could deliver a reversible capacity of 829 mA h g−1 at 42 mA g−1 for 50 cycles with a stable discharge plateaus ranging from 0.05–0.19 V versus Li+/Li. At higher rates of 420 and 840...
Significant progress is achieved for the utilization of graphene quantum dots as enzyme mimics in various biomedical fields recently. Although promising, the biocatalytic performance is far from satisfactory. Here, the rational design and synthesis of specific oxygenated groups enriched graphene quantum dots (o‐GQDs) via a facile oxidation reflux route is reported. These well‐prepared o‐GQDs with...
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