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AimAnticoagulants are commonly used to treat ischemic stroke. Its impact on cerebellar infarction has not been fully understood.
MethodsIn the clinical study, we reviewed a consecutive series of patients with large‐sized cerebellar infarction (diameter > 3 cm, n = 30) treated with or without anticoagulation. In animal study, cerebellar infarction operation was performed in 12 Cynomolgus monkeys...
SUMMARY Aims: To investigate the anticerebral ischemic properties of YGY‐E (apigenin‐7‐O‐β‐d‐glucopyranosy l‐4′‐O‐α‐L‐rhamnopy‐ranosid, a flavonoid glycoside extracted from plant phoenix‐tail fern), focusing on its effects on neuronal apoptosis. Methods:In vitro YGY‐E treatment was examined in primary cultured rat hippocampal neurons subjected to hypoxia‐reoxygenation (H‐R) injury. In addition, in vivo...
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