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Multiple sequence alignment is the most common task in computational biology. This multiple sequence alignment is computationally difficult and classified as a NP-Hard problem; so approximate algorithm(s) are generally required for most multiple alignment tasks. The Molecular Biologist may require the alignment of thousands of sequences that each can be of many hundreds of amino acids or even several...
G-rich DNA has been known to form a variety of folded and multistranded structures, with even single base modifications causing important structural changes. But, very little is known about the dynamic characteristics of the structures, which may play crucial roles in facilitating the structural transitions. In this background, we report here NMR investigations on the structure and dynamics of a DNA...
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