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TheRBMY(RNA-binding motif, Y chromosome) gene family encodes a germ-cell-specific nuclear protein implicated in spermatogenesis. It consists of approximately 30 genes and pseudogenes, found on both arms of the Y chromosome.RBMYshares high homology with an autosomalhnRNPGgene that contains an RNA-binding motif and one of the four SRGY repeats found inRBMY.One proposal is thatRBMYrepresents an ancestralhnRNPGgene,...
TheRBM(RNA-binding motif) gene family on the human Y chromosome encodes proteins with an RNA-binding domain. Its exclusive expression in germ cells and its partial deletion in some azoospermic or severely oligospermic males provide evidence of a role forRBMgenes in spermatogenesis. There are approximately 30RBMgenes, found on both arms of the Y chromosome. TwoRBMcDNA clones with slightly different...
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