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A label-free nanopore biosensor for detection of DNA target is proposed utilizing hybridization chain reaction (HCR) strategy for signal amplification. The DNA target triggered HCR to form large DNA nanostructure inside the nanopore and out the nanopore membrane, which inducing the ionic current decrease effectively due to the blockage of the nanopore. The developed method achieves a desirable sensitivity...
A novel method was developed for the analysis of monoamine neurotransmitters (MNTs) in human urine by carrier-mediated liquid-phase microextraction based on solidification of stripping phase method (CM-LPME-SSP) coupled with high performance liquid chromatography-electrochemical detector (HPLC-ECD). By adding an appropriate carrier in organic phase, simultaneous extraction of hydrophilic analytes,...
The quartz crystal microbalance (QCM) dynamic measurements indicate that ginsenoside Rh 2 (G-Rh 2 ) could inhibit the proliferation of adriamycin-resistant human breast cancer MCF-7 cells (MCF-7/ADR) in a concentration-dependent way. The combined treatment of G-Rh 2 with adriamycin (ADR) at non-effect dosage resulted in the higher inhibition efficiencies and the increased cell-death...
We have explored use of perfused regenerated cellulose (RC) microdialysis tubing (216μm o.d./200μm i.d.) as sampling probes for gaseous ammonia. The probes functioned by allowing the gas to diffuse through the permeable membrane into a stream of de-ionized water which continually perfused the tubing at 10–20μLmin −1 . The resulting ammonium in the perfusate was determined through a fluorimetric...
The electrochemical synthesis and characterization of a copolymer, poly(o-toluidine-co-o-aminophenol), were conducted using in situ piezoelectric FTIR spectroelectrochemisty. The monomer feed ratio strongly affects the copolymerization rate and the properties of the copolymer during the electrosynthesis in 0.5M H 2 SO 4 aqueous solution. The effects of scan rate and pH value on the...
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