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A novel cardiomimetic biohybrid material, termed as the human ventricular cardiac anisotropic sheet (hvCAS) is reported. Well‐characterized human pluripotent stem‐cell‐derived ventricular cardiomyocytes are strategically aligned to reproduce key electrophysiological features of native human ventricle, which, along with specific selection criteria, allows for a direct visualization of arrhythmic spiral...
Human (h) pluripotent stem cells (PSC) such as embryonic stem cells (ESC) can be directed into cardiomyocytes (CMs), representing a potential unlimited cell source for disease modeling, cardiotoxicity screening and myocardial repair. Although the electrophysiology of single hESC-CMs is now better defined, their multi-cellular arrhythmogenicity has not been thoroughly assessed due to the lack of a...
Thermal expansion of differently‐textured pyrolytic carbon matrices (pyrocarbons) of carbon/carbon composites was studied with a high temperature X‐ray diffraction at temperatures ranging from 25°C to 1400°C. The composites were synthesized by chemical vapor infiltration of a carbon fiber felt, using methane as a carbon source. From the linear dependence of the lattice displacement on temperature,...
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