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Cardiotoxicity is one of the most serious side effects of cancer chemotherapy. Current approaches to monitoring of chemotherapy‐induced cardiotoxicity (CIC) as well as model systems that develop in vivo or in vitro CIC platforms fail to notice early signs of CIC. Moreover, breast cancer (BC) patients with preexisting cardiac dysfunctions may lead to different incident levels of CIC. Here, a model...
In article number 2004258, Ali Khademhosseini, Su Ryon Shin, and co‐workers develop a model for investigating chemotherapy‐induced cardiotoxicity where induced pluripotent stem cell‐derived cardiac tissues are interacted with breast cancer tissues on a dual‐organ platform. Using electrochemical immuno‐aptasensors to monitor cell‐secreted multiple biomarkers, the proposed platform could be potentially...
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