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Nanoparticles have been studied as carriers that improve the absorption of peptides via the gastrointestinal tract. Many peptides are highly water soluble, however, hardly any nanoparticles are suitable for them. In this study, nanoparticles capable of encapsulating hydrophilic peptides were developed.Nanoparticles were prepared by the dispersion copolymerization of hydrophilic macromonomers such...
Nanoparticles have been studied extensively as carriers for oral delivery of peptides whose bioavailability is very low because of high hydrophilicity and instability in the gastrointestinal tract. This study evaluated the usefulness of nanoparticles composed of new graft copolymers having a hydrophobic backbone and hydrophilic branches, as carriers that enhance the absorption of peptides.Nanoparticles...
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