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Most xenobiotic estrogeniety assay methods rely on direct agonist action on the estrogen receptor (ER) to approximate activation potential. Such methods do have drawbacks since some ER activating pesticides are weak or non-agonistic in ligand-binding assays. This study discusses a method that detects pesticide estrogenic actions regardless of ER ligand binding ability. Using a serum-free BG-1 ovarian...
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