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ObjectivesTreatment discontinuation after long‐term bisphosphonate (BP), termed a ‘drug holiday’, has been proposed to reduce the risk of BP‐associated complications. The duration of treatment cessation remains unclear. Changes in bone mineral density (BMD), bone turnover markers (BTMs) and their relationship with FRAX were assessed to help determine the optimum length of a ‘drug holiday’.
MethodsA...
AimsTo assess treatment outcome in male patients with micro‐ and macroprolactinomas.
DesignMulticentre and retrospective study.
PatientsEighty‐eight male patients (15 micro‐ and 73 macroprolactinomas), aged 40·3 ± 14·7 years, were studied. Time of follow‐up ranged from 3 to 244 months.
MethodsClinical, hormonal and radiological data were registered at diagnosis and follow‐up. Treatment outcome...
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