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Since its introduction into North America in 1999, there have been over 10,000 confirmed cases of West Nile virus (WNV) neuroinvasive disease, and WNV has become by a large margin, the most common cause of arboviral encephalitis in the U.S. Since the ratio of asymptomatic WNV infections exceeds the number of neuroinvasive cases by ~150:1 it can be estimated that more than 1.5 million individuals have...
Summary Infections in the central nervous system (CNS) are caused by a wide range of microorganisms resulting in distinct clinical syndromes including meningitis, encephalitis, and pyogenic infections, such as empyema and brain abscess. Bacterial and viral infections in the CNS can be rapidly fatal and can result in severe disability in survivors. Appropriate identification and acute management of...
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