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Diffuse cutaneous mastocytosis (DCM) is an extremely rare disease characterized by massive proliferation of mast cells infiltrating the entire skin. We report a Chinese family with indolent DCM, and detection of a new germline KIT mutation located in the fifth immunoglobulin‐like loop of the KIT protein, which probably results in a gain‐of‐function effect and consequent overactivation of mast cells...
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