Search results for: M. Kang

Items from 1 to 20 out of 417 results

article

A cost analysis of MR‐guided laser interstitial thermal therapy for adult refractory epilepsy

Michael G. Brandel, Nikhita Kunwar, Ali A. Alattar, Keiko M. Kang, more

Epilepsia > 64 > 9 > 2286 - 2296

Objective MR‐guided laser interstitial thermal therapy (LITT) is used increasingly for refractory epilepsy. The goal of this investigation is to directly compare cost and short‐term adverse outcomes for adult refractory epilepsy treated with temporal lobectomy and LITT, as well as to identify risk factors for increased costs and adverse outcomes. Methods The National Inpatient Sample (NIS) was...

article

Febrile neutropenia management and outcomes in hematopoietic cell transplantation for chronic granulomatous disease

Mark Parta, Jennifer Cuellar‐Rodriguez, Juan Gea‐Banacloche, Jing Qin, more

Transplant Infectious Disease > 24 > 2 > n/a - n/a

Objective We analyzed events and therapies related to febrile neutropenia in patients receiving hematopoietic cell transplantation (HCT) for chronic granulomatous disease (CGD). Methods Three protocols for HCT were used to extract the relation between conditioning and infectious complications during transplantation for CGD, especially the relation of fever and neutropenia to microbiological events...

article

Development of a high‐resolution typing method for SLA‐3, swine MHC class I antigen 3

S. Youk, M.T. Le, M. Kang, B. Ahn, more

Animal Genetics > 53 > 1 > 166 - 170

We developed a high‐resolution and comprehensive typing method for swine leukocyte antigen 3 (SLA‐3), an MHC class I gene, employing locus‐specific genomic PCR followed by subsequent direct sequencing. A total of 292 individuals from nine pure, one cross‐breed and six cell lines were successfully typed. A total of 21 SLA‐3 alleles were identified, of which four were found to be novel alleles. However,...

article

Promoter engineering‐mediated Tuning of esterase and transaminase expression for the chemoenzymatic synthesis of sitagliptin phosphate at the kilogram‐scale

Taresh P. Khobragade, Seongseon Yu, Hyunsang Jung, Mahesh D. Patil, more

Biotechnology and Bioengineering > 118 > 8 > 3263 - 3268

Here, we report a bienzymatic cascade to produce β‐amino acids as an intermediate for the synthesis of the leading oral antidiabetic drug, sitagliptin. A whole‐cell biotransformation using recombinant Escherichia coli coexpressing a esterase and transaminase were developed, wherein the desired expression level of each enzyme was achieved by promotor engineering. The small‐scale reactions (30 ml) performed...

article

Display of quintuple glucagon‐like peptide 1 (28–36) nonapeptide on Bacillus subtilis spore for oral administration in the treatment of type 2 diabetes

M. Kang, F. Feng, Q. Ge, F. Zhu, more

Journal of Applied Microbiology > 130 > 2 > 314 - 324

Aims To develop an oral delivery system of glucagon‐like peptide 1 (GLP‐1) (28–36) for treating type‐2 diabetes, B.S‐GLP‐1(28–36), a recombinant Bacillus subtilis spores transformed with a plasmid vector encoding five consecutive GLP‐1 (28–36) nonapeptides with an enterokinase site was constructed. Methods and Results GLP‐1(28–36) nonapeptide was successfully expressed on the surface of B. subtilis...

article

Osteoporosis and bone health in autoimmune blistering skin disease—an evidenced based review

M. Kang, A. Bilgic, M. Radjenovic, D.F. Murrell

Journal of the European Academy of Dermatology and Venereology > 34 > 12 > 2745 - 2756

Autoimmune blistering skin diseases (AIBD) encompass a group of diseases characterised by cutaneous and/or mucocutaneous fragility. Multiple risk factors contributing to osteoporosis exist in AIBD patients, including use of long‐term systemic corticosteroid therapy (SCT), decreased mobility and the presence of chronic inflammation. Despite this, there is no consensus on the prophylaxis of osteoporosis...

article

Targeting of intragraft reactive oxygen species by APP‐103, a novel polymer product, mitigates ischemia/reperfusion injury and promotes the survival of renal transplants

Koichiro Minami, Soochan Bae, Hirofumi Uehara, Chen Zhao, more

American Journal of Transplantation > 20 > 6 > 1527 - 1537

Inflammatory responses associated with ischemia/reperfusion injury (IRI) play a central role in alloimmunity and transplant outcomes. A key event driving these inflammatory responses is the burst of reactive oxygen species (ROS), with hydrogen peroxide (H₂O₂) as the most abundant form that occurs as a result of surgical implantation of the donor organ. Here, we used a syngeneic rat renal transplant...

article

Altered monoamine levels in the dorsal striatum of the rat are associated with alterations in behavioural selection and motivation following peripheral nerve injury and acute stress

Gizem Gemikonakli, Kevin A. Keay, Michael D. Kendig, James W. M. Kang, more

European Journal of Neuroscience > 50 > 5 > 2786 - 2800

Chronic neuropathic pain and psychological stress interact to compromise goal‐directed control over behaviour following mild psychological stress. The dorsomedial (DMS) and dorsolateral (DLS) striatum in the rat are crucial for the expression of goal‐directed and habitual behaviours, respectively. This study investigated whether changes in monoamine levels in the DMS and DLS following nerve injury...

article

Generalized k-fractional integral inequalities associated with (α,m) $(\alpha ,m)$-convex functions

S. M. Kang, G. Farid, M. Waseem, S. Ullah, more

Journal of Inequalities and Applications > 2019 > 2019 > 1 > 1-14

This research investigates bounds of the sum of left-sided and right-sided fractional integrals in a compact form. These bounds are established by using (α,m) $(\alpha ,m)$-convex functions. The results of this paper also have connection with some known and already published results (Dragomir and Agarwal in Appl. Math. Lett. 11(5):91–95, 1998; Farid in J. Anal. 2018, https://doi.org/10.1007/s41478-0079-4;...

article

Gender difference in the impact of coexisting diabetes mellitus on long‐term clinical outcome in people with heart failure: a report from the Korean Heart Failure Registry

H.‐L. Kim, M.‐A. Kim, K.‐T. Park, D.‐J. Choi, more

Diabetic Medicine > 36 > 10 > 1312 - 1318

Aim Few data are available on the gender‐related differences in the prognostic impact of diabetes in people with heart failure. This study was performed to investigate whether there is a gender difference in the association between diabetes and long‐term clinical outcomes in people hospitalized for heart failure. Methods A total of 3162 people hospitalized with heart failure (aged 67.4 ± 14.1 years,...

article

Chronic Granulomatous Disease-Associated IBD Resolves and Does Not Adversely Impact Survival Following Allogeneic HCT

Rebecca A. Marsh, Jennifer W. Leiding, Brent R. Logan, Linda M. Griffith, more

Journal of Clinical Immunology > 2019 > 39 > 7 > 653-667

Introduction Inflammatory bowel disease (IBD) affects approximately 1/3 of patients with chronic granulomatous disease (CGD). Comprehensive investigation of the effect of allogeneic hematopoietic cell transplantation (HCT) on CGD IBD and the impact of IBD on transplant outcomes is lacking. Methods We collected data retrospectively from 145 patients with CGD who had received allogeneic HCT at 26...

article

Growth-promoting bioactivities of Bipolaris sp. CSL-1 isolated from Cannabis sativa suggest a distinctive role in modifying host plant phenotypic plasticity and functions

Lubna, A.L. Khan, M. Waqas, S.-M. Kang, more

Acta Physiologiae Plantarum > 2019 > 41 > 5

Endophytic fungi have been considered as strong plant growth promoters due to phytohormones production. The current study reports the isolation of endophytic fungi from bio-prospective medicinal plant cannabis sativa. Endophytic fungus Bipolaris sp. CSL-1 from the leaves of C. sativa was isolated. Culture filtrate (CF) was primarily investigated for indole-3-acetic acid (IAA) and gibberellins (GAs)...

article

Transfusion support for matched sibling allogeneic hematopoietic stem cell transplantation (1993–2010): factors that predict intensity and time to transfusion independence

Linda M. Griffith, Mark VanRaden, A. John Barrett, Richard W. Childs, more

Transfusion > 59 > 1 > 303 - 315

BACKGROUND Patients undergoing allogeneic hematopoietic stem cell transplant require variable, often extensive transfusion support. Identification of factors that predict urgent, intensive, or special needs should improve management of these patients. STUDY DESIGN AND METHODS This is a retrospective study of red blood cell (RBC) and platelet transfusion support provided for sequential matched sibling...

article

Data-driven inverse modeling with a pre-trained neural network at heterogeneous channel reservoirs

Seongin Ahn, Changhyup Park, Jaejun Kim, Joe M. Kang

Journal of Petroleum Science and Engineering > 2018 > 170 > C > 785-796

This paper develops a reliable and efficient data-integration method, based on artificial neural networks (ANN) incorporated with a stacked autoencoder (SAE) in a deep neural network's framework. To handle scale-different static and dynamic data of heterogeneous channel reservoirs, the workflow suggests an unsupervised pre-training process coupled with ANN-based inverse modeling. The performances...

article

Study of Thin Double-Gap RPCs for the CMS Muon System

K. S. Lee, S. W. Cho, S. Choi, B. Hong, more

Journal of the Korean Physical Society > 2018 > 73 > 8 > 1080-1087

High-sensitivity double-gap phenolic resistive plate chambers (RPCs) are studied for the Phase-2 upgrade of the Compact Muon Solenoid (CMS) muon system at high pseudorapidity η. Whereas the present CMS RPCs have a gas gap thickness of 2 mm, we propose to use thinner gas gaps, which will improve the performance of these RPCs. To validate this proposal, we constructed double-gap RPCs with two different...

article

Globular adiponectin acts as a melanogenic signal in human epidermal melanocytes

Y. Kim, J.Y. Cho, S.W. Oh, M. Kang, more

British Journal of Dermatology > 179 > 3 > 689 - 701

Background Adiponectin is an adipocyte‐derived cytokine that circulates as a full‐length protein and a fragment containing the globular domain of adiponectin (gAd). A recent study has reported the antimelanogenic effects of full‐length adiponectin. Objectives To examine the involvement of gAd in melanogenesis and its mechanisms of action. Methods The effects of gAd on melanogenesis and its mechanisms...

article

The partitioning of poleward energy transport response between the atmosphere and Ekman flux to prescribed surface forcing in a simplified GCM

Sarah M. Kang, Yechul Shin, Francis Codron

Geoscience Letters > 2018 > 5 > 1 > 1-10

Recent studies have indicated that ocean circulation damps the atmospheric energy transport response to hemispherically differential energy perturbations, thereby muting the shifts of the Inter-Tropical Convergence Zone (ITCZ). Here, we focus on the potential role of Ekman heat transport in modulating this atmospheric response. An idealized representation of Ekman-driven heat transport (F_E) is included...

article

Regulation of endogenous phytohormones and essential metabolites in frankincense-producing Boswellia sacra under wounding stress

A.L. Khan, A. Al-Harrasi, R. Shahzad, Q.M. Imran, more

Acta Physiologiae Plantarum > 2018 > 40 > 6

article

Effects of ultrasonic instrumentation on enamel surfaces with various defects

S‐Y Kim, M‐K Kang, S‐M Kang, H‐E Kim

International Journal of Dental Hygiene > 16 > 2 > 219 - 224

Objective The aim of this study was to analyse the enamel damage caused by ultrasonic scaling of teeth with various enamel conditions that are difficult to identify by visual inspection, such as enamel cracks, early caries and resin restorations. Methods In total, 120 tooth surfaces were divided into 4 experimental groups using a quantitative light‐induced fluorescence‐digital system: sound enamel...

article

On the Reverse Stability Kinetics of Meat Pigment Oxidation in Aqueous Extract from Fresh Beef

Jonghoon Kang, Albert M. Kang

Journal of Food Science > 83 > 4 > 879 - 880

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Search results for: M. Kang

A cost analysis of MR‐guided laser interstitial thermal therapy for adult refractory epilepsy

Febrile neutropenia management and outcomes in hematopoietic cell transplantation for chronic granulomatous disease

Development of a high‐resolution typing method for SLA‐3, swine MHC class I antigen 3

Promoter engineering‐mediated Tuning of esterase and transaminase expression for the chemoenzymatic synthesis of sitagliptin phosphate at the kilogram‐scale

Display of quintuple glucagon‐like peptide 1 (28–36) nonapeptide on Bacillus subtilis spore for oral administration in the treatment of type 2 diabetes

Osteoporosis and bone health in autoimmune blistering skin disease—an evidenced based review

Targeting of intragraft reactive oxygen species by APP‐103, a novel polymer product, mitigates ischemia/reperfusion injury and promotes the survival of renal transplants

Altered monoamine levels in the dorsal striatum of the rat are associated with alterations in behavioural selection and motivation following peripheral nerve injury and acute stress

Generalized k-fractional integral inequalities associated with (α,m) $(\alpha ,m)$-convex functions

Gender difference in the impact of coexisting diabetes mellitus on long‐term clinical outcome in people with heart failure: a report from the Korean Heart Failure Registry

Chronic Granulomatous Disease-Associated IBD Resolves and Does Not Adversely Impact Survival Following Allogeneic HCT

Growth-promoting bioactivities of Bipolaris sp. CSL-1 isolated from Cannabis sativa suggest a distinctive role in modifying host plant phenotypic plasticity and functions

Transfusion support for matched sibling allogeneic hematopoietic stem cell transplantation (1993–2010): factors that predict intensity and time to transfusion independence

Data-driven inverse modeling with a pre-trained neural network at heterogeneous channel reservoirs

Study of Thin Double-Gap RPCs for the CMS Muon System

Globular adiponectin acts as a melanogenic signal in human epidermal melanocytes

The partitioning of poleward energy transport response between the atmosphere and Ekman flux to prescribed surface forcing in a simplified GCM

Regulation of endogenous phytohormones and essential metabolites in frankincense-producing Boswellia sacra under wounding stress

Effects of ultrasonic instrumentation on enamel surfaces with various defects

On the Reverse Stability Kinetics of Meat Pigment Oxidation in Aqueous Extract from Fresh Beef

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