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Cell segmentation in microscopy imagery is essential for many biomedical applications. In this paper, a novel level set based technique is proposed for segmenting the differential interference contrast (DIC) red blood cell microscopy images. Based on the framework of subjective surfaces, a local complex phase based edge indicator function is introduced to replace the traditional gradient-based edge...
Segmentation of neural stem cells is the preliminary step to treat and cure several brain neural diseases. There exist a number of methods to accomplish this task. However, all of these methods suffer from some problems, such as high intensity variation sensitivity, human interaction and high computational complexity. In this paper we proposed a novel edge-detection-based neural stem cell image segmentation...
Automatic or semi-automatic segmentation and tracking of artery trees from computed tomography angiography (CTA) is an important step to improve the diagnosis and treatment of artery diseases, but it still remains a significant challenging problem. In this paper, we present an artery extraction method to address the challenge. The proposed method consists of two steps: (1) a geometric moments based...
Dendritic spines play an essential role in the central nervous system. Recent experiments have revealed that neuron functional properties are highly correlated with the statistical and morphological changes of the dendritic spines. In this paper, we propose a new multi scale approach for detecting dendritic spines in a 2D Maximum Intensity Projection (MIP) image of the 3D neuron data stacks collected...
Neuron image analysis has recently emerged as a critical component for enabling quantitative systems neurobiology and high throughput drug screening. In this paper, we present a new algorithm for fast and automatic extraction of neurite structures in microscopy neuron images. The algorithm is based on novel methods for soma segmentation, seed point detection, recursive center line detection, and 2D...
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