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We report on results of a localization ROC (LROC) study that evaluated several multiclass model observers as predictors of human tumor-detection performance. The study used image slices extracted from simulated whole-body FDG-PET volumes. Lesions were located in the liver, lungs, and soft tissue of a mathematical phantom, and the data simulation modeled a full-3D acquisition mode with an ECAT HR+...
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