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This is the first report of a transverse carbon nanoelectrode for sensing translation events through a solid state nanopore. This device has application to the study of molecular transport and DNA sequencing. The device is fabricated on a silicon nitride membrane using electron beam stimulated oxidation of carbon (EBSOC) to first create a carbon nanowire. The nanowire is then encapsulated in a top...
Marine dinoflagellates of the genus Alexandrium can produce dangerous amounts of paralytic shellfish toxins at such low cell densities that water discoloration often associated with harmful algal blooms is not always evident, making detection of blooms during early stages extremely important. Our research focuses on developing a new method of molecular detection for multiple species of Alexandrium...
Nanopore DNA sequencing devices show promise for rapidly decoding genetic information, although single nucleotide detection appears to be beyond the sensitivity of present transmembrane current measurement schemes. In this paper, a nanodevice combining nanoelectrodes with a nanopore was made to measure the nucleotide dependent transverse tunneling currents during the translocation of DNA through the...
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