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Background: During the therapy of tumor with IMRT, the main problem is how to select models of dose calculation and how to select optimization methods of inverse planning to deliver an accurate prescribe dose to the planning target volume while causing the least possible damage to surrounding organ at risk and normal tissue. Objective: To study the methods of beam parameters optimization to achieve...
This paper analyzed and compared the two kinds of objective function which based on dose and equivalent uniform dose (EUD).Both of them were applied to optimize the IMRT plan for lung cancer. The prescription dose for target was 80Gy, the tolerance dose for organ at risk and normal tissue were 30Gy and 50Gy. Genetic algorithm was selected and the population size, number of generation, mutation rate...
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