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In refractory epilepsy, the goal of neuroimaging is to localize the region of seizure onset. Tracers that accumulate and remain fixed proportional to regional cerebral blood flow (rCBF) at the time of injection are used to obtain SPECT images of the brain activity during and between seizures. The most used technique for detecting the epileptogenic zone (EZ) is to threshold the co-registered and normalized...
Changes in regional cerebral blood flow (rCBF) have been reported in idiopathic Parkinson's disease (PD). Nonetheless, their typical pattern still remains controversial regarding some features, such as basal ganglia involvement and the main cortical regions affected. Functional neuroimaging makes it possible to identify the brain dysfunctions of the neural circuits underlying the disease. Voxel-based...
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