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An elevated systolic blood pressure (SBP) response to a graded maximal exercise stress test (GEST) may be a predictor of endothelial dysfunction and hypertension. We examined relationships among the GEST peak SBP response and indicators of endothelial function.Men (n=48, 43.7±1.4yr) with high BP (145.1±1.5/85.5±1.1mmHg) completed a GEST. Peak SBP was the highest SBP achieved during the GEST. Blood...
A polymorphism (−786 T>C) in the promoter region of the endothelial nitric oxide synthase gene (eNOS) has important functional characteristics. We examined the influence of eNOS −786 T>C (rs2070744) on the BP and NO response to acute dynamic exercise.Subjects (n=49, 43.7±1.4yr) had pre- to Stage-1 hypertension (145.6±1.5/85.9±1.1mmHg). Volunteers performed three experiments; a non-exercise control...
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