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Lab-on-a-Chip (LOC) biomicrofluidic technologies are rapidly emerging bioanalytical tools that can miniaturize and revolutionize in situ research on embryos of small vertebrate model organisms such as zebrafish (Danio rerio) and clawed African frog (Xenopus laevis). Despite considerable progress being made in fabrication techniques of chip-based devices, they usually still require excessive and manual...
In recent years, Lab-on-a-Chip technology has been widely applied to the pharmaceutical and eco-toxicity domains, together with the use of zebrafish as the model organism for performing fish embryo toxicity assay. However, the requirement of constant human attention and lack of fully automated systems have lead into low throughput and slow turnaround time for the experiments. In this paper, a novel...
The zebrafish is a popular model organism that is widely applied with lab-on-a-chip (LoC) technology in drug discovery and toxicity assay experiments. In such experiments, constant human attention is required during and after the experiments for online and offline monitoring and analysis. The throughput and turnaround time are both hindered from lack of automated image analysis. In this paper, a novel...
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