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Cellular processes are regulated by various mechanical and physical factors in their local microenvironment such as geometric confinements, cell–substrate interactions, and cell–cell contact. Systematic elucidation of these regulatory mechanisms is crucial for fundamental understanding of cell biology and for rational design of biomedical devices and regenerative medicine. Here, we report a generally...
Collective cell motions play essential roles in the regulation of various complex biological processes such as embryogenesis, tissue regeneration, and carcinogenesis. In this study, we present a novel plasma lithography technique for creating surface functionalized confinements toward the investigation of collective cell migration. The ability to confine cells one-dimensionally using plasma lithography...
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