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Cysteinyl leukotrienes are involved in ischemic brain injury, and their receptors (CysLT 1 and CysLT 2 ) have been cloned. To clarify which subtype mediates the ischemic neuronal injury, we performed permanent transfection to increase CysLT 1 and CysLT 2 receptor expressions in PC12 cells. Oxygen glucose deprivation (OGD)-induced cell death was detected by Hoechst 33258...
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