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There is an increasing interest in bubble-mediated focused ultrasound (FUS) interventions in the brain. However, current technology lacks the ability to spatially monitor the interaction of the microbubbles with the applied acoustic field, something which is critical for safe clinical translation of these treatments. Passive acoustic mapping could offer a means for spatially monitoring microbubble...
A 32 element receiver array was designed and integrated into an existing 1372 element transcranial therapy array to introduce real-time treatment monitoring capabilities. A semi-randomized array layout allowed signals from a narrowband source to be detected and localized within the array field of view. The combined array was used to sonicate microbubbles and detect their emissions both directly and...
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