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PurposeMRI‐guided high intensity focused ultrasound (MR‐HIFU) allows noninvasive heating of deep tissues. Specifically targeting visceral fat deposits with MR‐HIFU could offer an effective therapy for reversing the development of obesity, diabetes, and metabolic syndrome.
MethodsOverweight rats received either MR‐HIFU of visceral fat, sham treatment, no treatment, or ex vivo temperature calibration...
Noninvasive molecular imaging of angiogenesis could play a critical role in the clinical management of peripheral vascular disease patients. The ανβ3‐integrin, a well‐established biomarker of neovascular proliferation, is an ideal target for molecular imaging of angiogenesis. This study investigates whether MR molecular imaging with ανβ3‐integrin‐targeted perfluorocarbon nanoparticles can detect the...
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