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Amphotericin B (AmB) is a life-saving antibiotic, used to treat deep-seated mycotic infections. Both the therapeutic and toxic side effects of AmB are directly dependent on its molecular organization. Organization of AmB was studied in monocomponent monomolecular layers formed at the argon–water interface, by means of polarized and non-polarized electronic absorption spectroscopy and analyzed in terms...
Amphotericin B (AmB) is a polyene antibiotic used to treat deep-seated mycoses. Both the therapeutic action and the toxic side effects of this drug are dependent on its molecular organization. AmB appears as a zwitterion at neutral pH owing to NH 3+ and COO − groups. The results obtained with electronic absorption, fluorescence, resonance light scattering and infrared absorption...
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