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The interleukin (IL)‐6/IL‐6 receptor‐α (IL‐6Rα)/signal transduction and activation of the transcription 3 (STAT3) pathway plays an important role in inflammation. Anti‐human IL‐6Rα blockade by tocilizumab (TCZ) has been used in pig‐to‐baboon organ xenotransplant models, but whether it is beneficial remains uncertain. After xenotransplant, there were significant increases in both baboon and pig IL‐6...
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